Addressing challenges when implementing PFAS LC-MS analysis methods for water samples

Due to their widespread use and persistence in the environment, the determination of PFAS in various matrices, including water, has become one of the most pressing environmental and human health topics of recent years. LC-MS/MS is firmly established as a key analytical technique used to assess their prevalence both in the natural and human environments. However, PFAS analysis by LC-MS is a highly complex and challenging application, due to potentially thousands of target PFAS components, exceptionally low (ppt) detection necessary, varying regulatory requirements and strong potential for the contamination of samples during collection and processing. This webinar draws on experience and challenges encountered in our own lab from setting up targeted LC-MS/MS methods for the analysis of PFAS in water samples. It is aimed to provide guidance to analysts new to, or in the initial stages, of implementing PFAS analysis and will cover topics including:

•  What are PFAS?
• Analytical setup, including delay column use. 
• Identifying and controlling sources of exogenous sample contamination in the lab

For more information, please contact us at webinar@avantorsciences.com