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TAE684 ≥95%

Supplier: Adipogen
Description: TAE684 is a potent and selective ALK inhibitor with an IC(50) of 3nM. It is 100-fold more sensitive for ALK over InsR.

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RG7422 ≥95%

Supplier: Adipogen
Description: GDC-0980 (RG7422) is a selective, dual PI3 Kinase and mTOR Kinase inhibitor with IC(50) values of 5, 27, 7, and 14nM for PI3Kalpha-delta respectively. It inhibits mTOR with a Ki of 17nM.

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MLN0128 ≥95%

Supplier: Adipogen
Description: MLN0128 is a potent and selective mTOR inhibitor with an IC(50) of 1nM; <gt/>200-fold less potent to class I PI3K isoforms, superior in blocking mTORC1/2 and sensitive to pro-invasion genes (vs Rapamycin).

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N-Boc-N′-succinyl-4,7,10-trioxa-1,13-tridecanediamine ≥95%

Supplier: Adipogen
Description: Bifunctional linker for chemical synthesis.

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2-(Tosyloxy)cycloheptanone ≥97%

Catalog Number: (102991-132)
Supplier: Adipogen
Description: Building block for synthesis.
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1,2,3-Tris(diethylamino)cyclopropenylium bis(trifluoromethanesulfonyl)imide ≥97%

Supplier: Adipogen
Description: Air- and water-stable ionic liquid. The properties of these ionic liquids include almost zero vapour pressure, low flammability and ease of recycling. They are frequently considered as potential green alternatives to classical organic solvents. Additionally, most classes can be readily tuned to provide unique solvent environments in which to carry out reactions, extractions and other processes. There are a large number of applications.

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meso-Tetraphenyl-tetrabenzoporphine palladium complex ≥97%

Supplier: Adipogen
Description: Phosphorescent probe for measuring oxygen in very low concentrations. Luminescent marker for oxygen and pH in biomedical imaging. Used as sensitizer in the process of photon up-conversion based on triplet–triplet annihilation (TTA). Used as agent for PDT, optical limiters and other types of nonlinear optical materials.

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n-Tetradecanoyl-L-homoserine lactone ≥97%

Supplier: Adipogen
Description: N-Tetradecanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. It appears later than shorter acyl chain AHLs in developing biofilms and, like other long chain AHLs, stimulates bacterial growth. C14-HSL also alters the proteolytic activity and enhances the migration of some strains of Proteus mirabilis. Induces violacein expression in a Chromobacterium violaceum mutant usually not able to produce homoserine lactones.

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3,3',5,5'-Tetramethylbenzidine dihydrochloride

Supplier: Adipogen
Description: TMBZ is a chromogenic reagent utilized for peroxidase detection. It has been developed as an alternative to benzidine. Although the TMBZ solution is colorless, it turns bluish-green (lambdamax: 655 nm) in the presence of hydrogen peroxide and peroxidase. The structure of this bluish-green complex is thought to be a radical form of two oxidized TMBZ molecules. This peroxidase substrate is used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA). The substrate produces a soluble end product that is pale blue in color and can be read spectrophotometrically at 370 or 620-650 nm. The TMB reaction may be stopped with 2M H2SO4 (resulting in a yellow color), and read at 450nm.

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6-(Dimethylamino)purine

Catalog Number: (102989-766)
Supplier: Adipogen
Description: A puromycin analog that acts as a protein kinase inhibitor. Selectively induces premature mitosis in mammalian cells. Inhibits TNF-alpha upregulation of ICAM-1, lipolysis, and the activation of JNK/SAPK. Inhibits p34cdc2/cyclin B (IC50 = 300 µM). Induces apoptosis in S-phase-arrested HeLa cells (~5 mM).
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DAR-4 ≥98%

Supplier: Adipogen
Description: Photo-stable fluorescent probe for the detection of nitric oxide (NO).

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2,4-Difluororesorcinol

Supplier: Adipogen
Description: Fluorinated building block for dye synthesis. Key precusor for preparing Pacific Blue dyes. Precursor that can be used for preparing fluorescent dyes such as fluorescein, coumarin and resorufin analogs.

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SAR-131675 ≥95%

Supplier: Adipogen
Description: SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells with IC(50) values of 20 and 45nM, respectively. SAR131675 dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD, with an IC(50) of about 20nM. SAR131675 was found to be highly selective for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. However, it was moderately active on VEGFR-2 with a VEGFR-3/VEGFR-2 ratio of about 10. SAR131675 had no antiproliferative activity on a panel of 30 tumors and primary cells, further showing its high specificity and indicating that SAR131675 is not a cytotoxic or cytostatic agent.

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2,5-Bis(4-aminophenyl)-1,3,4-oxadiazole

Supplier: Adipogen
Description: Fluorescent stain for DNA.

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5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate N-succinimidyl ester (CDCFDA) ≥96%

Supplier: Adipogen
Description: 5-(and-6)-Carboxy-2',7'-dichlorofluorescein diacetate, succinimidyl ester is a useful fluorescent tracer that can passively diffuse into cells and covalently label intracellular proteins, resulting in long-term cell labeling. The reagent itself is colorless and nonfluorescent but becomes brightly green fluorescent once it is hydrolyzed by intracellular esterases.

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CCVJ ≥97%

Supplier: Adipogen
Description: Fluorescent probe for binding to proteins etc. quantum yield increases by decreasing free rotation. Fluorescent molecular rotor.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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