Key challenges and potential solutions for eliminating bottlenecks and optimizing biopharma downstream processes

Finding efficiencies across downstream processing steps and cost-effectively aligning the productivity of downstream production with upstream yields require complex analysis and optimisation. This presentation elaborates on the key aspects of downstream processing, looking at different areas where improvements by new techniques and new technologies could be made, from current process chromatography technologies, new powder and liquid handling strategies to raw material data analysis.

This presentation was given during Bioprocessing Summit Virtual, March 16 - 17, 2021.     

Presented by:

Willie Hesselink, Senior Technical Application Project Manager, Biopharma Production, Avantor Willie Hesselink is Senior Technical Application Project Manager at Avantor´s biopharma production unit. Prior to this role, he was R&D Manager at Avantor Performance Materials. Willie brings over 20 years of industrial expertise in the R&D of raw materials + excipients for biopharma processes. In his current role, he has led many process optimization and TCO projects in collaboration together with clients. Willie holds a B.Sc. in analytical chemistry from the Saxion Univ. of Applied Sciences in Enschede, Netherlands.