PP2B control protein-GST fusion
- Control Protein
- PCA Assays
- ImmunoBlot
PP2B is a key regulator of the anaphase-promoting factor which is an excellent substrate for protein phosphatase. PP2B is involved in bovine ocular tissues and is postulated to be involved in the immunologic privilege of the cornea, in retinal signal transduction, and in the toxic effects of immunosuppressants on the eye. PP2B acts as an inhibitory constraint on I-LTP that is relieved by PKA, and that this inhibitory constraint acts as a gate to regulate the synaptic induction of L-LTP (1). PP2B plays a role in the transition from short- to long-term memory and also regulates bone formation through an effect on osteoblast differentiation (2). PP2B Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Metabolic Disorder, Phosphatases, and Ser/Thr Kinases research.
PP2B Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. PP2AB Protein is suitable for use in Western Blot. Expect a band approximately ~83kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.