ADAM17 Fluorometric Drug Discovery Kit, Enzo Life Sciences

Supplier: Enzo Life Sciences

BML-AK310-0001

76002-366EA 670 USD

76002-366

ADAM17 Fluorometric Drug Discovery Kit, Enzo Life Sciences

Assays Protein Assays

Designed to screen ADAM17 (TACE) inhibitors using a quenched fluorogenic peptide. The ADAM17 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen ADAM17 (TACE) inhibitors using a quenched fluorogenic peptide: Mca-PLAQAV-Dpa-RSSSR-NH2. Mca fluorescence is quenched by the Dpa group until cleavage by proteases separates the two moieties. The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of ADAM17, a potential therapeutic target. The compound GM6001 is also included as a prototypic control inhibitor.

Ordering information: Contains 1 vial ADAM17 enzyme, 1 vial Substrate (Mca-PLAQAV-Dpa-RSSSR-NH2), 1 vial DMSO, 1 vial CALIBRATION STANDARD, 1 vial control inhibitor (GM6001), 1 bottle (20 ml) assay buffer, 1 black 96-well microplate, Instructions.

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