Q-VD-OPh

Supplier: ADIPOGEN CORP MS

AG-CP3-0006-M001 AG-CP3-0006-3001 AG-CP3-0006-M005
102988-448EA 228.46 USD
102988-448 102988-450 102988-452
Q-VD-OPh
Proteins and Peptides

Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains.


Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Used in apoptosis and inflammasome studies.

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