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Human Recombinant EGF (from CHO Cells)

Supplier: Peprotech

100-15R-500UG 100-15R-1MG

10778-872EA 3761.17 USD

10778-872 10778-874

Human Recombinant EGF (from CHO Cells)

Proteins and Peptides

EGF Receptor (EGFR, ErbB1) is a transmembrane protein that exerts tyrosine kinase activity upon ligand-induced activation. EGFR can be activated by binding EGF, or at least six other structurally related protein ligands, including TGFα, HB-EGF, Betacellulin (BTC), Amphiregulin, Epiregulin, and Epigen. Upon activation, EGFR initiates a signaling cascade, which includes dimerization and internalization, tyrosine phosphorylation, DNA synthesis of target genes and, ultimately, cell proliferation. EGFR signaling plays a role in the growth and differentiation of normal cells, but elevated EGFR activity is correlated with the development and pathogenesis of certain cancers. Recombinant Human EGF Receptor (EGFR) is a 621 amino acid glycoprotein comprising the extracellular domain of EGFR, and migrates at an apparent MW of 97.5 kDa by SDS-PAGE analysis under reducing conditions.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

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