Human Recombinant SCD40 Ligand (from E. coli)

Supplier: Peprotech

AF-310-02-10UG AF-310-02-50UG AF-310-02-100UG AF-310-02-250UG AF-310-02-500UG AF-310-02-1MG
10778-748EA 181.47 USD
10778-748 10778-750 10778-752 10778-754 10778-756 10778-758
Human Recombinant SCD40 Ligand (from E. coli)
Proteins and Peptides

CD40, a member of the TNF receptor superfamily, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells.  Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching.  The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes.  Failure to express CD40L leads to “immunodeficiency with hyper-IgM”, a disease characterized by failure to produce IgG, IgA and IgE.  The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain.  The soluble form of CD40L is an 18 kDa protein comprising the entire TNF homologous region of CD40L and is generated in vivo by an intracellular proteolytic processing of the full length CD40L.  Recombinant Human soluble CD40 ligand is a 16.3 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L. Manufactured using all Animal-Free reagents.


  • Carrier free
  • Animal-free


MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LWLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL


Verified by N-terminal and Mass Spectrometry analyses (when applicable).


Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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