Human Recombinant MIF (from Hi-5 Insect Cells)

Supplier: Peprotech

300-69-5UG 300-69-25UG 300-69-100UG 300-69-250UG 300-69-500UG 300-69-1MG
10774-142EA 143.41 USD
10774-142 10774-144 10774-146 10774-148 10774-150 10774-152
Human Recombinant MIF (from Hi-5 Insect Cells)
Proteins and Peptides

Macrophage migration inhibitory factor (MIF) is a small secreted protein that can act as a pleiotropic pro-inflammatory cytokine, as well as an enzyme. MIF pro-inflammatory activity can be initiated by signaling through CD74 and CD44, resulting in the secretion of TNF-a, IL-1, IL-6, IL-8, and variousmMPs. The enzymatic activity of MIF is characterized by its ability to act as a tautomerase, capable of catalyzing the keto-to-enol isomerization of keto-phenylpyruvate and L-dopachrome. It appears as though MIF catalytic activity is dependent upon a trimeric configuration and a free N-terminal proline residue. Insect cell-derived Recombinant Human MIF is a 15 kDa protein containing 124 amino acid residues, including an N-terminal His-tag.


Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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