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Product Image-77392-572

Ultrasolute™ Amphipol 17

Supplier: 0000042190
Description: The Ultrasolute family evolved from the first amphipol A8-35 is used for highly efficient solubilization and stabilization of membrane proteins without the use of detergents while preserving their activity. They demonstrate tolerance to moderate concentrations of divalent cations and exhibit no absorption at wavelengths >250 nm.

Product Image-77392-592

Sulfo-SMA Membrane protein solubilization & stabilization

Supplier: 0000042190
Description: Sulfo-SMA is an electroneutral modification of existing SMAs. It does not interfere with charge-sensitive interactions between proteins and lipids. This innovation opens up a wider range of experimental research in terms of charge-sensitive membrane protein processes like protein-protein and protein-lipid interactions. In addition, Sulfo-SMA belongs to a new generation of SMA’s which are RAFT polymerized. This achieves a reduction in both monomer size and greater monodispersity.
Another significant advantage of Sulfo polymers compared to other polymers is the wide pH range in which they remain stable. The buffer in which the polymer is supplied has a pH of 7.5, but the polymer itself remains stable between pH 4 and pH 10.
The special physicochemical properties of Sulfo-SMAs make them ideal for cryo-TEM and other downstream applications.
After successful membrane protein solubilization, the protein can be purified using affinity chromatography. For membrane protein purification, we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
Good publications to find details about Sulfo-SMA and Sulfo-DIBMA are:
Glueck et al. (2022)
Janson et al. (2022)
Eggenreich et al. (2023)

Product Image-77392-754

Nanodisc MSP2N2 POPC

Catalog Number: (77392-754)
Supplier: 0000042190
Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
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Nanodisc Assembly Kit MSP1D1-His POPC

Catalog Number: (77392-688)
Supplier: 0000042190
Description: This product is a MSP nanodisc assembly kit. It contains a vial of lyophilized membrane scaffold protein MSP1D1 (His-tagged) and a vial of DMPC or POPC phopshospholipid to assemble a MSP nanodisc.
Product Image-77392-676

Human Recombinant MSP1E3D1 (from E. coli)

Supplier: 0000042190
Description: Membrane scaffold protein, human origin.

Product Image-77392-732

Nanodisc MSP1D1 dH5 DMPG

Catalog Number: (77392-732)
Supplier: 0000042190
Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
Product Image-77393-072

HighSpec HighSpec Rho1D4 MagBeads

Supplier: CUBE BIOTECH
Description: HighSpec Rho1D4 MagBeads are a suspension of 30 µm magnetic agarose beads coupled to an anti-Rho1D4 antibody.

Product Image-77393-590

PureCube Zn-NTA MagBeads

Supplier: CUBE BIOTECH
Description: PureCube Zn-NTA magnetic beads/MagBeads were developed by Cube Biotech for His-tag protein purification.

Product Image-77393-108

PureCube HiCap StrepTactin® Compact Cartridge

Supplier: CUBE BIOTECH
Description: HiCap StrepTactin® Compact Cartridge is a FPLC-ready column that is pre-packed with our PureCube HiCap StrepTactin® agarose resin.

Product Image-77393-368

PureCube NHS Activated Agarose XL

Supplier: CUBE BIOTECH
Description: PureCube NHS (N-hydroxy succinimide) agarose XL resin is your best option to couple biomolecules carrying free-standing amine groups.

Product Image-77393-064

HighSpec Rho1D4 Agarose

Supplier: CUBE BIOTECH
Description: HighSpec Rho1D4 Agarose resin is a suspension of 40 µm agarose beads, coupled to an anti-Rho1D4 antibody. It is meant for protein purification assays of the highest possible purity, exploiting the specificity of an antibody to its antigen.

Product Image-77393-142

PureCube Octyl Agarose

Supplier: CUBE BIOTECH
Description: Our PureCube octyl agarose resin is a suspension of purification beads for Hydrophobic Interaction Chromatography (HIC).

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Miltefosine ≥99.5%, Crystallization grade

Supplier: 0000042190
Description: Phosphocholines, or Fos-cholines, are a novel class of detergents that is well suited for the solubilization, stabilization, and purification of membrane proteins. For screening of the best-suited detergent for a given application, we offer Fos-cholines with chain lengths from C-9 to C-16.

Image Unavailable-77392-486

PureCube DIBMA Glucosamine, Screening Kit, HEPES

Catalog Number: (77392-486)
Supplier: 0000042190
Description: DIBMA stands for diisobutylene maleic acid copolymer, and is an extensively researched polymer. The fundamental properties of DIBMA include the absence of light absorption at a wavelength >250 nm, a crucial factor for protein detection via absorbance, and a high resistance to divalent cations.
Product Image-77392-768

Nanodisc MSP1E3D1-His POPC Biotinyl PE

Catalog Number: (77392-768)
Supplier: 0000042190
Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
Product Image-77392-772

Mouse Recombinant MSP1D1-His (from E. coli)

Supplier: 0000042190
Description: Membrane scaffold protein, mouse origin.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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