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5(6)-ROX N-succinimidyl ester ≥95% (by HPCE)

Supplier: Adipogen
Description: 5-(and-6)-Carboxy-X-rhodamine, succinimidyl ester is an amine-reactive long wavelength rhodamine dye. Derivatives made with the amine-reactive carboxy-X-rhodamine (ROX), succinimidyl ester are widely used for oligonucleotide labeling and automated DNA sequencing applications. Conjugates of this dye have longer-wavelength spectra than the spectra of Lissamine rhodamine B conjugates, but somewhat shorter-wavelength spectra than those of Texas Red® conjugates.

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Human Recombinant CD278 (from CHO Cells)

Supplier: Adipogen
Description: CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.

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Concanamycin B (from Streptomyces species) ≥98% (by HPLC), high purity

Supplier: Adipogen
Description: Concanamycin B inhibits proliferation of mouse splenic lymphocytes.

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Betulinic Acid

Supplier: Adipogen
Description: Anti-HIV compound. Anticancer compound. Apoptosis inducer. Modulator of NF-kappaB. Potent DNA topoisomerase II inhibitor. Potent proteasome activator. Antimalarial compound.

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Dihydroethidium

Supplier: Adipogen
Description: Redox indicator. Blue fluorescence until oxidized to ethidium. Can be used for detecting superoxide radical in cells, tissues and organisms.

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Alcian blue 8GX 50% (by UV/Vis)

Supplier: Adipogen
Description: Alcian blue 8GX is primarily used for demonstrating acid mucopolysaccharides, which it does quite selectively. In recent years there has been some difficulty obtaining the dye. Alcian Blue 8GX is also suitable for detection of glycoproteins on nitrocellulose and in PAGE gels. There are other dyes similar to alcian blue, although not necessarily belonging to the same class of dyes. Alcian green has gained some popularity, and alcian yellow has been suggested, especially in a method for demonstrating Helicobacter. They are used for acid mucopolysaccharides in the same way as alcian blue. They have no particular advantage for demonstrating mucin. According to the Merck Index the groups marked X split off during staining.

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Amuvatinib ≥95%

Supplier: Adipogen
Description: Amuvatinib is a potent, novel and orally active multi-targeted tyrosine kinase inhibitor, which inhibits a number of validated tumor targets including c-kit, PDGFRalpha and flt3, with IC(50) values of 10nM, 40nM and 81nM respectively.

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Human CD275 (from CHO cells)

Catalog Number: (102513-368)
Supplier: Adipogen
Description: The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology), and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.

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6-IAF ≥95% (by HPLC)

Supplier: Adipogen
Description: Fluorescent reagent with high selectivity.

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Propidium iodide

Supplier: Adipogen
Description: Propidium iodide is the most common red-fluorescent nuclear stain. It can also be excited using excitation filters appropriate for green-fluorescent dyes.

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NAD Synthetase (from E. coli)

Catalog Number: (102980-452)
Supplier: Adipogen
Description: NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways
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8-Acetoxypyrene-1,3,6-trisulfonic acid trisodium salt

Supplier: Adipogen
Description: Highly water soluble enzyme substrate for the fluorometric assay of esterases at longer wavelengths.

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Human Recombinant VEGF 165 (from Insect Cells (Sf9))

Supplier: Adipogen
Description: Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo. It is also a chemoattractant molecule for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.

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RO-3306 ≥95% (by NMR)

Supplier: Adipogen
Description: Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Potential anti-cancer compound. Cell cycle arrest inducer at G1, S and G2/M·Apoptosis inducer in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Enhances Fas-mediated activation and processing of procaspase-8 in mitotic cells towards.

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Boromycin ≥99% (by TLC)

Supplier: Adipogen
Description: Boron-containing macrolide antibiotic

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AMCA-H N-succinimidyl ester ≥90% (by HPLC)

Supplier: Adipogen
Description: AMCA-H NHS ester reacts with primary amine groups on antibodies, proteins, peptides and other biomolecules at pH 7.0-9.0. Suitable for labeling lysyl residues in proteins (Ex/Em: 353/455nm).

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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