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Catalog Number: (MSPP-100-0676)
Supplier: STEMCELL Technologies
Description: The SARS-CoV-2 (spike protein) peptide pool is provided as two lyophilized mixtures (subpools) from the SARS-CoV-2 spike protein. Each subpool contains 158 peptides, for a total of 316 peptides. The virus attaches to the cell membrane of the host through the interaction between spike protein and angiotensin-converting enzyme 2 (ACE2) receptor, and the spike protein plays a critical role in viral entry. The subpools consist of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 1273 on the spike protein.

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Catalog Number: (MSPP-100-1324)
Supplier: STEMCELL Technologies
Description: Use autotaxin (ENPP2) to catalyze the production of lysophosphatidic acid (LPA), a potent mitogen that can evoke growth factor-like responses (Moolenaar and Corven), from lysophospholipids in extracellular fluids. Autotaxin is a secreted glycoprotein that belongs to the ectonucleotide pyrophosphatase/phosphodiesterase (ENPP) family, containing two N-terminal somatomedin B (SMB)-like domains, a central phosphodiesterase (PDE) domain with an active catalytic site, and a C-terminal nuclease-like (NUC) domain (Nishimasu <i>et al.</i>). Dysregulation of autotaxin and LPA receptors is implicated in cancer (Tigyi <i>et al.</i>), fibrosis (Ninou <i>et al.</i>), neurological disorders (Roy <i>et al.</i>), and other inflammation-associated conditions. Both Autotaxin and LPA are overexpressed in many cancers and can promote cell proliferation, migration, and resistance to apoptotic death (Tigyi <i>et al.</i>). Autotaxin was also found to catalyze the production of cyclic phosphatidic acid (CPA), an analog of LPA, which has anti-mitogenic and inhibitory effects on tumor cell invasion and metastasis (Fujiwara). This protein contains a His-residue tag at the amino end of the polypeptide chain. For consistency and reproducibility across your applications, Autotaxin from STEMCELL comes lyophilized with ≥ 85% purity, and endotoxin levels are verified to be ≤1.0 EU/μg protein.

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Supplier: STEMCELL Technologies
Description: Dickkopf-related protein 1 (DKK-1) is a member of the Dickkopf family and is a secreted protein that inhibits the canonical WNT pathway by competitive binding to low-density lipoprotein receptors (LRP)-5 and 6 with high affinity, thereby decreasing β-catenin protein stability (Niehrs). DKK-1 regulates embryonic development and contains two conserved cysteine-rich domains separated by a linker region and an N-terminal signal peptide (Krupnik <i>et al.</i>; Lieven <i>et al.</i>). A family of human DKK-related genes composed of DKK-1, DKK-2, DKK-3, and DKK-4 have been characterized together with a unique DKK-3 related protein termed Soggy (Krupnik <i>et al.</i>). DKK-1 has been shown to support the generation of myeloid-derived suppressor cells (MDSCs) and thus is a negative regulator of antitumor immune responses (D’Amico <i>et al.</i>). DKK-1 from thrombocytes is an important regulator of leukocyte infiltration and induces Th2 cell polarization and potentiates Th2 cell cytokine expression (Chae <i>et al.</i>). DKK-1 has also been shown to drive cardiac and retinal differentiation from induced pluripotent stem (iPS) cells (Lian <i>et al.</i>). Protein contains a His-residue tag at the carboxyl end of the polypeptide chain.

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Catalog Number: (MSPP-05925)
Supplier: STEMCELL Technologies
Description: Integrated workflow containing tools to isolate and expand CD34+ progenitor cells from peripheral blood and their subsequent reprogramming to iPS cells.

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Catalog Number: (MSPP-100-0190)
Supplier: STEMCELL Technologies
Description: Cell culture medium for establishment and maintenance of human colorectal cancer organoids.

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Supplier: STEMCELL Technologies
Description: Immunomagnetic isolation of untouched human peripheral blood mononuclear cells from whole blood

Supplier: STEMCELL Technologies
Description: For depletion of red blood cells from fresh blood samples and isolation of nucleated cells.

Supplier: STEMCELL Technologies
Description: Immunomagnetic isolation of untouched mouse plasmacytoid dendritic cells (pDC)

Catalog Number: (MSPP-10975)
Supplier: STEMCELL Technologies
Description: Culture supplement for the differentiation of human naïve CD4+ T cells into Th2 cells.


Catalog Number: (MSPP-19656)
Supplier: STEMCELL Technologies
Description: Immunomagnetic isolation of eosinophils directly from whole blood


Catalog Number: (MSPP-100-0711)
Supplier: STEMCELL Technologies
Description: Culture medium kit for expansion of human NK cells.


Catalog Number: (MSPP-100-0712)
Supplier: STEMCELL Technologies
Description: Serum-free and xeno-free base medium for the expansion of NK cells.


Catalog Number: (MSPP-17754)
Supplier: STEMCELL Technologies
Description: Immunomagnetic positive selection of particle-free human CD19+ cells.


Catalog Number: (MSPP-09600)
Supplier: STEMCELL Technologies
Description: Serum-free medium for culture and expansion of hematopoietic cells.


Catalog Number: (MSPP-07156)
Supplier: STEMCELL Technologies
Description: For neural differentiation of mouse and human ES and iPS cells.


Supplier: STEMCELL Technologies
Description: Immunodensity isolation of untouched NK cells.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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