You Searched For: STEMCELL Technologies

Catalog Number: (MSPP-28110)

Supplier: STEMCELL Technologies

Description: Ideal for safe and accurate handling of methylcellulose-based media. Blunt end reduces the risk of needle stick injuries.

Supplier: STEMCELL Technologies

Description: Medium for the culture and differentiation of human monocytes into dendritic cells and their maturation.

Catalog Number: (MSPP-37250)

Supplier: STEMCELL Technologies

Description: Hank's Balanced Salt Solution (HBSS) can be used for diluting, washing, irrigating or as a transporting solution for cell or tissue culture. It provides a buffering system to maintain the physiological pH range and osmotic balance of culture media, and provides cells with a source of water and essential inorganic ions and a carbohydrate as an energy source.

Catalog Number: (MSPP-10953)

Supplier: STEMCELL Technologies

Description: Supplement for the differentiation of mouse naïve CD4+ T cells into Th1 cells.

Catalog Number: (MSPP-100-0691)

Supplier: STEMCELL Technologies

Description: Defined supplement for improving survival of human ES and iPS cells in single-cell workflows.

Supplier: STEMCELL Technologies

Description: Interleukin 15 (IL-15) is a four-alpha helix bundle cytokine with many similar properties to IL-2, with which it shares components of its receptor. The IL-15 receptor is a heterotrimeric receptor composed of IL-15Ra, the high-affinity receptor for IL-15, as well as IL-2/15Rb (CD122) and common gamma chain (CD132). IL-15 binds to IL-15Rα receptor and can then be presented in trans to IL-2/15Rb and common gamma chain on other cells. Trans-presentation is thought to be the major mechanism by which IL-15-mediated responses occur in mice, although may not be necessary in humans (Castillo <i>et al.</i>). The cytoplasmic domains of IL-2/15Rb and common gamma chain mediate signaling to activate JAK/STAT and PI3K pathways. IL-15 supports the survival and proliferation of naive CD4+ and CD8+ T cells, and promotes homeostasis of memory T cells. IL-15 also promotes the survival and differentiation of NK cells and regulates their cytolytic activity (Ma <i>et al.</i>).

Catalog Number: (MSPP-18970)

Supplier: STEMCELL Technologies

Description: Immunomagnetic positive selection of CD11b+ cells (e.g. monocytes) from mouse splenocytes or other tissues.

Catalog Number: (MSPP-08600)

Supplier: STEMCELL Technologies

Description: Differentiation kit for the generation of neuronal precursors from human ES and iPS cell-derived neural progenitor cells.

Supplier: STEMCELL Technologies

Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages. In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda <i>et al.</i>). GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 cells (Francisco-Cruz <i>et al.</i>). The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton <i>et al.</i>). GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells. GM-CSF is able to stimulate the development of DCs that ingest, process, and present antigens to the immune system (Francisco-Cruz <i>et al.</i>).

Catalog Number: (MSPP-07159)

Supplier: STEMCELL Technologies

Description: For coating tissue cultureware to promote cell adherence.

Supplier: STEMCELL Technologies

Description: Interferon-gamma (IFN-γ), also known as type II interferon, is produced by T and NK cells, and in smaller amounts by dendritic cells and macrophages. IFN-γ is controlled by cytokines such as IL-12 and IL-18 secreted in response to infection (Schroder <i>et al.</i>). IFN-γ binds to a receptor complex and initiates signal transduction via the JAK/STAT pathway; this culminates in the transcription and activation of many genes that control a diverse array of immunological functions (de Weerd and Nguyen; Krause <i>et al.</i>). IFN-γ stimulates the antimicrobial and anti-tumor activity of macrophages, NK cells, and neutrophils (Billiau and Matthys) by promoting the activation of microbial effector functions such as production of reactive oxygen species, nitric oxide, and complement (Schroder <i>et al.</i>). IFN-γ enhances MHC class I and II expression in dendritic cells and mononuclear phagocytes, as well as the production of IL-12 by dendritic cells. In B cells, IFN-γ stimulates survival and growth in both mouse and human cells, and redirects B cells from proliferation towards differentiation. IFN-γ favors the development of Th1 vs Th2 cells and stimulates monocyte differentiation and function (Schroder <i>et al.</i>).

Catalog Number: (MSPP-07005)

Supplier: STEMCELL Technologies

Description: Support cell attachment, growth, and proliferation with CellAdhere™ Type I Collagen, Human, Lyophilized. The most abundant type of collagen in the human body, type I collagen is a natural extracellular matrix protein that provides structural support and mimics physiological conditions, making it an ideal cultureware coating surface to support cell attachment in 2D applications.

Catalog Number: (MSPP-03806)

Supplier: STEMCELL Technologies

Description: Polyethylene glycol reagent for hybridoma fusion.

New Product

Catalog Number: (MSPP-19867)

Supplier: STEMCELL Technologies

Description: Immunomagnetic isolation of untouched myeloid-derived suppressor cells (CD11b+Gr1+).

New Product

Catalog Number: (MSPP-100-0338)

Supplier: STEMCELL Technologies

Description: Apoptosis staining and detection kit - 100 tests.

New Product

Supplier: STEMCELL Technologies

Description: Column-free immunomagnetic positive selection of human CD8+ cells for HLA analysis.

New Product