You Searched For: SOUTHERN BIOTECHNOLOGY MS

Catalog Number: (100245-800)

Supplier: Southern Biotechnology

Description: FITC Anti-Human IgG4 pFc' antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.

Catalog Number: (100245-688)

Supplier: Southern Biotechnology

Description: Biotin Anti-Human IgG Fc antibody for use in ELISA, flow cytometry, immunohistochemistry, western blotting, and multiplex assays.

Catalog Number: (100246-100)

Supplier: Southern Biotechnology

Description: CD8 is a 33 kDa transmembrane glycoprotein expressed as either a CD8αα homodimer or CD8αβ heterodimer. It is expressed on the “cytotoxic/suppressor” subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC class I-restricted TCR’s in antigen recognition.

Catalog Number: (100245-652)

Supplier: Southern Biotechnology

Description: Purified Anti-Human IgM antibody for use in ELISA, flow cytometry, western blotting, and stimulation assays.

Catalog Number: (101442-866)

Supplier: Southern Biotechnology

Description: Goat Anti-Chicken IgY(H+L)-Biotin antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

Catalog Number: (101442-752)

Supplier: Southern Biotechnology

Description: CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P-selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes.

Catalog Number: (101442-520)

Supplier: Southern Biotechnology

Description: Mouse IgA-APC/CY7 for use as a control in flow cytometry assays.

Catalog Number: (100242-644)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG1-Texas Red antibody with minimal reactivity to human proteins for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.

Catalog Number: (100242-530)

Supplier: Southern Biotechnology

Description: Goat F(ab')2 Anti-Mouse IgG(H+L)-PE antibody with minimal reactivity to human proteins for use in flow cytometry assays.

Catalog Number: (100242-784)

Supplier: Southern Biotechnology

Description: AP Anti-Mouse IgE antibody for use in ELISA, immunohistochemistry, western blotting, and ELISpot assays.

Catalog Number: (100242-882)

Supplier: Southern Biotechnology

Description: Purified Anti-Mouse Kappa antibody for use in ELISA, flow cytometry, immunocytochemistry, and western blotting assays.

Catalog Number: (100242-162)

Supplier: Southern Biotechnology

Description: Purified Human IgG for use as a control in multiplex and microarray assays and as a standard in ELISA.

Catalog Number: (100242-182)

Supplier: Southern Biotechnology

Description: Human IgA Kappa-AP for use as a control in ELISA assays.

Catalog Number: (100242-738)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG3-TRITC antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry assays.

Catalog Number: (100243-024)

Supplier: Southern Biotechnology

Description: CD106, also known as VCAM-1, is an adhesion molecule and a major mediator of the inflammatory response. It is expressed on activated microvascular endothelial cells in response to signals arising from immune responses in infection, graft rejection, tumor recognition and killing. The complementary binding ligand for VCAM-1 is VLA-4/CD49d. In addition to VCAM-1, VLA-4 also recognizes the extracellular matrix molecule fibronectin. This pairing of VCAM-1 and VLA-4 is able to provide a second signal (e.g., non-antigen specific) for T cell stimulation, such as that seen in transplantation. The monoclonal antibody MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. In addition to inflammatory responses, VCAM-1 has a significant role in hemopoiesis through its ability to retain lymphocyte and myeloid precursors on stromal cells in the marrow and lymphoid organs. CD106/VCAM-1 exists as an integral membrane protein. The M/K-2 monoclonal antibody immunoprecipitates a peptide that gives a single band on SDS-PAGE gels with an apparent Mr of ~100 kDa under reducing conditions and 92 kDa under non-reducing conditions.

Supplier: Southern Biotechnology

Description: The TCRγδ heterodimer of the CD3/T cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of γδ TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are γδ+ and have limited receptor diversity. The TCRγδ heterodimer recognizes peptide antigen bound to MHC antigens and subsequent signal transduction mediated by the invariant chains leads to T cell activation. The monoclonal antibody UC7-13D5 is specific for the γδ heterodimer and plate-bound UC7-13D5 activates γδ TCR-bearing cells. This antibody does not react with αβ TCR-expressing T cells.