You Searched For: SOUTHERN BIOTECHNOLOGY MS

Catalog Number: (100245-758)

Supplier: Southern Biotechnology

Description: AP Anti-Human IgA1 antibody for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.

Catalog Number: (100245-770)

Supplier: Southern Biotechnology

Description: AP Anti-Human IgA2 antibody for use in ELISA, immunohistochemistry, western blotting, and ELISpot assays.

Catalog Number: (101442-638)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG2a-APC/CY7 antibody with minimal reactivity to human proteins for use in flow cytometry assays.

Catalog Number: (100245-694)

Supplier: Southern Biotechnology

Description: FITC Anti-Human IgG Fc antibody for use in flow cytometry and western blotting assays.

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Catalog Number: (100245-436)

Supplier: Southern Biotechnology

Description: The monoclonal antibody TCR-1 precipitates a heterodimer of Mr 90 kDa (two bands of Mr 50 kDa and 40 kDa upon reduction) on chicken peripheral blood T cells. Deglycosylation of the heterodimer yields two polypeptides of Mr 35 kDa and 32 kDa. Unlike human and mouse in which γδ cells comprise a minor subset of T lymphocytes in the circulation, the chicken has a relatively large subset of γδ T cells. The frequency of TCRγδ cells is typically 20-25% of the total blood T cells but may reach approximately 50% in chickens of six- months of age. The majority of TCRγδ+ cells in the thymus and blood are CD4-CD8- although a small subset of them may express CD8 or CD4 coreceptors. However, when the TCRγδ+ cells migrate into the spleen and intestine most of them begin to express CD8. Although the biological function of γδ T cells is unclear, they are clearly capable of cytotoxic activity in vitro. The CD8+ γδ T cells may also be involved in down-regulation of the immune response. They cannot, however, induce a graft-vs-host (GVH) reactions.

Catalog Number: (100245-480)

Supplier: Southern Biotechnology

Description: Chicken CD45 is a transmembrane glycoprotein expressed on all leukocytes. B lineage cells in the bursa of Fabricius express the 215 kDa isoform while T lineage cells bear the 190 kDa variant. These high molecular weight molecules have intrinsic phosphotyrosine phosphatase activity characteristic of mammalian CD45. Levels of CD45 expression detected by the monoclonal antibody LT40 in the avian thymus are heterogeneous with approximately 90% of thymocytes expressing fourfold higher levels of surface CD45 (CD45hi) than do the remaining 10% (CD45low) of thymocytes. The CD45low population contains exclusively thymocytes with the CD3-CD4-CD8low phenotype characteristic of the immediate precursors to the CD3-CD4+CD8+ thymic population which are CD45hi. This shift from low to high levels of surface CD45 expression is concomitant with the transition from CD4-CD8low to CD4+CD8+ and before the expression of CD3. The ability of the monoclonal antibody LT40 to discriminate this CD45low subpopulation provides a suitable marker for the CD3-CD4-CD8low immediate precursors to the CD3-CD4+CD8+ thymocytes.

Catalog Number: (100245-550)

Supplier: Southern Biotechnology

Description: Like their mammalian counterparts, avian MHC Class I molecules, also known as B-F antigens, consist of a highly polymorphic α-chain noncovalently bound to the invariant β2-microglobulin subunit. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes which are usually cytotoxic T cells. The monoclonal antibody F21-21 also reacts with turkey β2-microglobulin.

Catalog Number: (100245-524)

Supplier: Southern Biotechnology

Description: PE Anti-Chicken IgY antibody for use in flow cytometry assays.

Catalog Number: (100245-462)

Supplier: Southern Biotechnology

Description: CD4 is a type I transmembrane glycoprotein expressed on approximately 70% of thymocytes, 10% of spleen cells, and 45% of peripheral blood lymphocytes but less than 1% of bursal cells.

Catalog Number: (100245-162)

Supplier: Southern Biotechnology

Description: Purified Rabbit Anti-Mouse IgG(H+L) antibody for use in ELISA, immunohistochemistry, western blotting, immunoprecipitation, and ELISpot assays.

Catalog Number: (100245-206)

Supplier: Southern Biotechnology

Description: Goat Anti-Rhesus IgG(H+L)-TRITC antibody for use in immunocytochemistry assays.

Catalog Number: (100245-002)

Supplier: Southern Biotechnology

Description: Goat Anti-Hamster IgG(H+L)-AP antibody with minimal reactivity to mouse and rat proteins for use in ELISA, immunohistochemistry, and western blotting assays.

Catalog Number: (100244-946)

Supplier: Southern Biotechnology

Description: Rabbit F(ab')2 Anti-Goat IgG(H+L)-AP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.

Catalog Number: (100245-164)

Supplier: Southern Biotechnology

Description: Rabbit Anti-Mouse IgG(H+L)-FITC antibody for use in immunohistochemistry and western blotting assays.

Catalog Number: (100245-168)

Supplier: Southern Biotechnology

Description: Rabbit Anti-Mouse IgG(H+L)-HRP antibody for use in ELISA, immunohistochemistry, western blotting, and ELISpot assays.

Catalog Number: (100244-868)

Supplier: Southern Biotechnology

Description: The monoclonal antibody 74-22-15 reacts with > 90% of porcine monocytes and granulocytes and < 5% of peripheral blood lymphocytes.