You Searched For: SOUTHERN BIOTECHNOLOGY MS

Catalog Number: (101442-686)

Supplier: Southern Biotechnology

Description: Purified Anti-Mouse IgG2a antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and multiplex assays.

Catalog Number: (100242-472)

Supplier: Southern Biotechnology

Description: Purified Anti-Mouse IFN-gamma antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, ELISA, and ELISpot assays.

Catalog Number: (100242-342)

Supplier: Southern Biotechnology

Description: Purified Anti-Human IL-7 antibody for use in ELISA and immunocytochemistry assays.

Catalog Number: (100242-420)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgM-TRITC antibody for use in immunohistochemistry / immunocytochemistry assays.

Catalog Number: (100242-640)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG1-AP antibody with minimal reactivity to human proteins for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.

Catalog Number: (100244-036)

Supplier: Southern Biotechnology

Description: The monoclonal antibody 14-4-4S reacts with the I-Ek class II alloantigen on cells from mice of the H-2d, H-2p, and H-2r haplotypes. Cells from mice of the H-2b, H-2f, H-2q, and H-2s haplotypes do not express I-E antigen. The antibody has been reported to cross-react with the rat MHC class II alloantigen RT1D.

Catalog Number: (100243-842)

Supplier: Southern Biotechnology

Description: The monoclonal antibody HBF-719 reacts with the B6 allele of Ly49F, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been downregulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The HBF-719 antibody stains ~11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month old) to 10.0% (11 month old) of CD8+ spleen cells from C57BL/6 mice.

Supplier: Southern Biotechnology

Description: CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. The monoclonal antibody 6D5 recognizes the same epitope as the published clone, 1D3.

Supplier: Southern Biotechnology

Description: CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types and is now classified as a costimulatory molecule. The CD24 molecule, also known as HSA, is composed mostly of carbohydrate with a protein core of only 31-35 amino acids in the human and 27 amino acids in the mouse. CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins. Studies with purified CD24 applied to latex beads have demonstrated a self-binding property suggesting that the molecule is capable of promoting homotypic aggregation, binding, and cell adhesion. This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with an anti-CD24 monoclonal antibody. Recent studies of murine CD24 have assigned a role for CD24 as a ligand for P-selectin, a calcium-dependent lectin.

Catalog Number: (100244-222)

Supplier: Southern Biotechnology

Description: Goat Anti-Human IgM-Biotin antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, ELISpot, and multiplex assays.

Catalog Number: (100244-306)

Supplier: Southern Biotechnology

Description: Goat F(ab')2 Anti-Human IgG-Biotin antibody with minimal reactivity to mouse proteins for use in ELISA and flow cytometry assays.

Catalog Number: (100244-262)

Supplier: Southern Biotechnology

Description: Goat Anti-Human IgG-FITC antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

Catalog Number: (100244-182)

Supplier: Southern Biotechnology

Description: The 3C4 monoclonal antibody reacts with the cell surface glycoprotein mouse CD102 (ICAM-2), a ligand for the leucocyte integrin CD11a/CD18 (LFA-1). CD102 is constitutively expressed on T cells, B cells, and at high levels on vascular endothelial cells. It is also expressed on a variety of leukocyte cell lines. The 3C4 antibody blocks the interaction between ICAM-2 and LFA-1.

Catalog Number: (100244-750)

Supplier: Southern Biotechnology

Description: Purified Goat Anti-Rabbit IgG antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

Catalog Number: (100244-802)

Supplier: Southern Biotechnology

Description: The monoclonal antibody RDR34 reacts with RLA-DR-transfected cells but not with RLA-DQ-transfected cells. In normal adult rabbits, the antibody reacts with 50-60% of peripheral blood leukocytes and splenocytes. It has also been reported that the antibody stains lymphocytes in the thymic medulla and some cells in the cortex, periportal cells in the liver, and synovial lining cells (e.g., infiltrating macrophages) in inflamed synovium. DRα transcripts have been detected in appendix, bone marrow, spleen, and to a lesser extent in lymph nodes, lung, liver, and other organs.

Catalog Number: (100246-264)

Supplier: Southern Biotechnology

Description: CD43, a member of the sialomucin family of cell surface receptors, is a 95-135 kDa type I transmembrane glycoprotein whose variability in molecular weight is dependent upon the nature of the extracellular O-glycans. It is the major sialoglycoprotein on thymocytes, T cells, and neutrophils. It is also present on activated B cells, plasma cells, NK cells, granulocytes, monocytes, macrophages, platelets, and bone marrow hematopoietic stem cells. CD43, which binds to ICAM-1 (CD54), appears to function as an anti-adhesion molecule, inhibiting T cell interactions including T cell killing, and by increasing the threshold for T cell activation.