HERC4

Supplier: Rockland Immunochemicals

009-001-S02 009-001-S02S

75934-388EA 714 USD

75934-388 75934-386

HERC4

Proteins and Peptides

HERC4 control protein-GST fusion

Control Protein
PCA Assays
ImmunoBlot

HERC4 or HECT and RLD domain containing E3 ubiquitin protein ligase 4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD domain is predicted to act as a guanine nucleotide exchange factor for small G proteins (1). HERC4 is highly expressed in adult and fetal brain and in all specific brain regions examined (2). HERC4 Protein is ideal for investigators involved in Signaling Proteins, Ubiquitin Proteins, Cancer, Cell Cycle, Cytoplasmic Tyrosine Kinases, and Neurobiology research.

HERC4 is stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. HERC4 Protein is suitable for use in Western Blot. Expect a band approximately ~71kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

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