DNAJB1

Supplier: Rockland Immunochemicals

009-001-E57 009-001-E57S

75928-762EA 714 USD

75928-762 75928-760

DNAJB1

Proteins and Peptides

HSP40 control protein-GST fusion

Control Protein
PCA Assays
ImmunoBlot

HSP40 is a member of heat shock proteins (HSPs) which are synthesized in cells in response to heat shock and other metabolic stresses and provide a transient state of thermotolerance. HSP40 is localized faintly throughout the cell in non-heat-shocked cells and accumulates in the nuclei and nucleoli in heat-shocked cells (1). The intracellular localization of HSP40 is very similar to that of HSP70. Overexpression of HSP40 reduces aggregate formation and suppresses apoptosis in a neuronal cell model of spinal and bulbar muscular atrophy (inherited neurodegenerative diseases caused by polyglutamine expansion) (2). HSP40 is ideal for investigators involved in Signaling Proteins, Cell Stress & Chaperone Proteins, Cancer, Cellular Stress,and Inflammation research.

HSP40 Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. HSP40 Protein is suitable for use in Western Blot. Expect a band approximately ~65kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

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