Human Recombinant Bmp2k (from Baculovirus (Sf9 Insect cells))

Supplier: Rockland Immunochemicals

009-001-R53S 009-001-R53

10800-402EA 364 USD

10800-402 10800-404

Human Recombinant Bmp2k (from Baculovirus (Sf9 Insect cells))

Proteins and Peptides

BMP2K or Bone morphogenic protein 2 inducible kinase is the human homolog of mouse BMP-2-inducible kinase which plays a key role in skeletal development and patterning. BMP2K is a serine/threonine protein kinase which contains a nuclear localization signal and plays a regulatory role in attenuating the program of osteoblast differentiation. BMP2K gene is strongly correlated with high myopia and may contribute to a genetic risk factor for high degrees of myopic pathogenesis (1). BMP-2 expression is suppressed by an EP4 receptor antagonist and PGE2 produced by COX-2 increases BMP-2 expression via binding the EP4 receptor (2). BMP2K Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, AKT/PKB Pathway, Cancer, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, JNK/SAPK Pathway, NfkB Pathway, p38 Pathway, PKA/PKC Pathway, and WNT Signaling research.

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