[Lys(Ac)4]-Histone H3 (1-21)-GGK,Biotin

Supplier: AnaSpec
AS-65207-1
103009-042EA 599.23 USD
103009-042
[Lys(Ac)4]-Histone H3 (1-21)-GGK,Biotin
Proteins and Peptides
This peptide is histone H3 with acetylation at Lys4. It is biotinylated through a C-terminal GGK linker. This post-translationally modified histone peptide is found in humans, Tetrahymena thermophila, Schizosaccharomyces pombe , and mice. Acetylation at Lys4 is controlled by Mst1. This peptide acts as a chromodomain switch by weakening the interaction between Chp1 and the H3K9 methylated tail, thus facilitating binding of HP1 proteins. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ART-K(Ac)-QTARKSTGGKAPRKQLA-GGK(biotin)
MW:2765.3 Da
% peak area by HPLC:95
Storage condition:-20° C
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