520 MMP FRET Substrate XV, QXL™ 520-FAM, AnaSpec

Supplier: AnaSpec
AS-60582-01
103005-944EA 312.77 USD
103005-944
520 MMP FRET Substrate XV, QXL™ 520-FAM, AnaSpec
Proteins and Peptides
Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 7, 8, 12, 13 and 14 activities, Abs/Em = 494/521 nm.
Sequence:QXL™ 520 -γ-Abu-PQGL-Dab(5-FAM)-AK-NH2
MW:1647.7 Da
% peak area by HPLC:95
Storage condition:-20° C
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