R428 ≥95%
Supplier: ADIPOGEN CORP MS
SYN-1131-M001
SYN-1131-M005
SYN-1131-M010
102992-254EA
373.85
USD
102992-254
102992-256
102992-258
R428 ≥95%
R428
R428 is a selective inhibitor of the receptor tyrosine kinase AXL. R428 blocks the catalytic and procancerous activities of AXL in vitro. 428 inhibits AXL at low nanomolar values and blocked AXL-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Reported IC(50) values are 11-14nM .
Formula:
C₃₀H₃₄N₈ Storage Temperature: Freezer |
MDL Number:
MFCD21608463 CAS Number: 1037624-75-1 |
Specification Test Results
Purity |
|
Appearance/Color | Solid. |
Solubility | Soluble in DMSO or ethanol. |
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