Borrelidin (from Streptomyces species) ≥98% (by HPLC)

Supplier: ADIPOGEN CORP MS

BVT-0098-C500 BVT-0098-M001 BVT-0098-M005

102513-544EA 110.77 USD

102513-544 102513-546 102988-886

Borrelidin (from Streptomyces species) ≥98% (by HPLC)

Borrelidin

Borrelidin is a bacterial, protozoan and mammalian threonyl-tRNA synthetase (THrRS) inhibitor.

Macrolide antibiotic
Inhibitor of potato scab disease
Cyclin-dependent kinase (CDK) inhibitor

Antiangiogenic (IC50 = 0.8 nM) and anticancer agent. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Blocks the formation of spontaneous lung metastases of B16-BL6 melanoma cells. Antiviral. Potent antimalarial agent (IC50 = 0.97 nM).

White to off-white powder

After reconstitution protect from light at -20°C. Stable for at least one year after receipt when stored at -20°C.

Soluble in DMSO or methanol.

Formula: C₂₈H₄₃NO₆
MW: 489.7 g/mol
Storage Temperature: Freezer

CAS Number: 7184-60-3

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