Anti-FAS Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences
ADI-AAP-221-D ADI-AAP-221-F
95043-770EA 286.67 USD
95043-770 95043-772
Anti-FAS Rabbit Polyclonal Antibody
Antibodies
Fas/APO-1/CD95 is a 36 kDa cell surface type I-membrane glycoprotein with an apparent molecular weight of 44 kDa on SDS-PAGE.  Fas belongs to the tumor necrosis factor receptor (TNFR) family, which includes TNFR1, TNFR2, CD27, CD30 and CD40.  Binding of Fas-ligand (FasL) to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies leads to apoptosis of Fas expressing cells.  Both Fas and TNFR contain a 70 amino acid cytoplasmic “death domain” responsible for transmitting signals for apoptosis.  Apoptosis induced by Fas-Fas ligand interaction is inhibited by a number ofMore Product Information
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