Rat C-Peptide 1 Trifluoroacetate

Supplier: Bachem
4045921.0500 4045921.1000
H-6136.1000BAEA 1098.81 USD
H-6136.1000BA H-6136.0500BA
Rat C-Peptide 1 Trifluoroacetate
Proteins and Peptides
Synthesized prosequences from insulin.

Studies of the cellular effects of C-peptide have shown that it binds specifically in a nanomolar concentration range to a G-protein coupled membrane receptor, with subsequent activation of Ca²⁺-dependent intracellular signaling pathways. This resulted in stimulation of both Na⁺-K⁺-ATPase, and endothelial nitric oxide synthase activities. Administration of C-peptide to streptozotocin induced diabetic rats elicited a substantial increase in whole-body glucose turnover.
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