Anti-Apurinic/Apyrimidinic Endonuclease Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences
804-213-R100
89153-866EA 866.55 USD
89153-866
Anti-Apurinic/Apyrimidinic Endonuclease Mouse Monoclonal Antibody
Antibodies
Mammalian apurinic/apyrimidinic (AP) endonuclease (APE1; APEX; HAP1; Ref-1) is a multifunctional, bipartite enzyme that belongs to the class II AP endonucleases and that plays an important role in numerous, cellular functions, like repairing abasic sites (loss of purine or pyrimidine base) in DNA, regulating the redox state of other proteins that play roles in oxidative signalling, transcription factor regulation (Fos, Jun, NF-κ B, Myb, HIF-1α, CREB, Pac), cell cycle control (p53) and apoptosis. APE1 initiates the DNA base excision repair (BER) by cleaving the DNA immediately adjacent to theMore Product Information
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