Anti-RIPK1 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical
600-401-EA2
75931-632EA 635.22 USD
75931-632
Anti-RIPK1 Rabbit Polyclonal Antibody
Antibodies
RIP1 (Receptor Interacting Protein), also known as RIPK1, is a crucial 74 kD adaptor kinase in several of stress-induced signaling pathways and on the crossroad of a cell’s decision to live or die. RIP1 contains an N-terminal region with homology to protein kinases, an intermediate domain capable of association with MAPKKK and a C-terminal region containing a death domain motif present in the Fas and TNFR1 intracellular domains. Full length RIP1 is important for signallling to NF-kappa-B, MAPKs and necrosis, whereas caspase-8 generates a C-terminal RIP1 cleavage fragment, promoting TNF-More Product Information
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