Anti-RC3H1 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical
600-401-DX2
75931-492EA 635.22 USD
75931-492
Anti-RC3H1 Rabbit Polyclonal Antibody
Antibodies
The ring finger protein RC3H1, also known as Roquin, is a highly conserved member of the RING type ubiquitin ligase protein family whose M199R mutation leads to the excessive production of follicular helper T cells and germinal centers in the sanroque strain of mice, a strain with excessive IL-21 production and high titers of autoantibodies. The complete loss of RC3H1 induces early death and immune deregulation but not autoimmunity in RC3H1-null mice, suggesting that the mutant RC3H1 is more disruptive to the immune system than its complete loss.

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SPECIFICATIONS

Antigen Symbol RC3H1
Environmentally Preferable
Antibody Type Primary
Clonality Polyclonal
Reactivity
Host Rabbit
Isotype
Western Blot Yes
ELISA Yes
Purification Affinity purified
Storage Temperature Store vial at –20 °C. Aliquot contents and freeze at –20 °C. Centrifuge product if not completely clear after standing at room temperature. Stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.
Shipping Temperature 70

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