Anti-ORAI3 Mouse Monoclonal Antibody [Clone: [2H2G9]]

Supplier: Rockland Immunochemical
200-301-DH4
75930-646EA 739.7 USD
75930-646
Anti-ORAI3 Mouse Monoclonal Antibody [Clone: [2H2G9]]
Antibodies
Antigen stimulation of immune cells triggers Ca++ entry t hrough Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo aMore Product Information
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