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Bovine Collagen Type I (Insoluble)

Catalog Number: (103700-682)

Supplier: ADVANCED BIOMATRIX, INC. MS

Description: Type I bovine collagen, lyophilized fibrous powder is extracted from bovine flexor tendon with the raw material sourced from closed/controlled herds of animals. Because the collagen is extracted from tendon, the material is more naturally crosslinked. The collagen is polymeric insoluble collagen. The manufacturing processes comply with stringent quality standards that have proven to yield a high quality product with lot-to-lot consistency. This product has a purity of >96% with Type II and Type III collagens not detectable.

This product is supplied as a lyophilized fibrous powder in a 1 gram package size. Bioburden and endotoxin levels are tested – this product is not considered sterile.

This collagen product is naturally cross-linked yielding a robust material for applications which require structure and strength. This product can be readily prepared into such forms as tissue scaffolds, foams, sponges, suspensions, coatings, putties, films and sheets but does not form hydrogels. Using typical cross-linking methods, this material can be tuned for optimal in vivo resorption. This collagen product is ideal for tissue engineering applications and uses with inorganic and biomaterials.

The product is provided in user-friendly packaging for use and storage. Avoid extended exposure to ambient environment since this material is hygroscopic.

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Polyethylene glycol diacrylate (PEGDA), Extralink®-Lite

Supplier: ADVANCED BIOMATRIX, INC. MS

Description: Extralink-Lite PEGDA is a thiol-reactive crosslinker designed for use in HyStem kits.

Thiol-Modified Gelatin, Gelin-S, Advanced BioMatrix

Catalog Number: (103792-942)

Supplier: ADVANCED BIOMATRIX, INC. MS

Description: Gelin-S is a thiol-modified gelatin that comes as a lyophilized powder. Gelin-S is a component of the HyStem®-C and HyStem®-HP kits, but can be purchased separately here.

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VitroCol® Human Collagen

Catalog Number: (103700-642)

Supplier: ADVANCED BIOMATRIX, INC. MS

Description: Advanced BioMatrix VitroCol® collagen is the first widely available, naturally produced purified human collagen for research purposes. VitroCol® sets the standard for purity (>99% collagen content), functionality and represents the only native-like human collagen offered.

VitroCol® collagen is naturally secreted from human neo-natal fibroblast cells. The human fibroblasts are cultured in optimal conditions allowing the fibroblast to naturally and efficiently secret extracellular matrix. The extracellular matrix is then processed and purified to yield the naturally produced human collagen.

VitroCol® is approximately 97% Type I human collagen with the remainder being comprised of Type III collagen. It contains a high monomer content as measured by gel permeation chromatography.

VitroCol® is supplied at approximately 3 mg/ml concentration. The concentration for each specific lot is provided on a Certificate of Analysis that is available with the purchase of each product. VitroCol® is soluble atelo-collagen in 0.01 N HCI, therefore, the pH is approximately 2.0.

VitroCol® is especially ideal for human cell culture systems when coating of surfaces, providing preparations of thin layers of culturing cells, or use as a solid gel. VitroCol® human collagen is provided in user-friendly packaging for use and storage. VitroCol® is sterile filtered and is supplied as a ready to use solution.