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Catalog Number: (76544-170)
Supplier: Cayman Chemical Company
Description: A Certified Reference Material


Catalog Number: (75817-172)
Supplier: Cayman Chemical Company
Description: A complete system for quantifying complex I inhibition.


Catalog Number: (76544-326)
Supplier: Cayman Chemical Company
Description: A Certified Reference Material


Catalog Number: (76544-270)
Supplier: Cayman Chemical Company
Description: A Certified Reference Material


Catalog Number: (75816-762)
Supplier: Cayman Chemical Company
Description: Simple, reproducible, and sensitive tool for measurement of glycerol in plasma and serum.


Catalog Number: (76544-384)
Supplier: Cayman Chemical Company
Description: A Certified Reference Material


Catalog Number: (76544-144)
Supplier: Cayman Chemical Company
Description: A Certified Reference Material


Catalog Number: (76544-636)
Supplier: Cayman Chemical Company
Description: A Certified Reference Material


Catalog Number: (76544-226)
Supplier: Cayman Chemical Company
Description: A Certified Reference Material


Supplier: Cayman Chemical Company
Description: A competitive assay that can be used for quantification of 2-methoxyestradiol in plasma, urine, and other sample matrices.

Catalog Number: (75817-250)
Supplier: Cayman Chemical Company
Description: A competitive assay for rapid screening for His-tagged proteins.


Supplier: Cayman Chemical Company
Description: A fluorometric detection assay for hydrogen peroxide.

Catalog Number: (76293-148)
Supplier: Cayman Chemical Company
Description: Stimulator of interferon genes (STING) is a component of the innate immune response that binds to cyclic dinucleotides, which are bacterial second messengers, leading to activation of NF-κB and transcription of immunomodulatory genes, including type I interferon (IFN). The R232 variant is the most common variant in the human population, found at a frequency of 57.9% in the 1000 Genome Project.{38697} The SNP variant H232 (Item No. 22815) is found at a 13.7% frequency. Various mutations in STING either reduce or increase its activity. Gain-of-function mutations in STING, including R284M (Item No. 23594) and V155M, lead to constitutive activation and enhancement of the type I IFN response. The V155M mutation is associated with a systemic inflammatory condition, including pulmonary fibrosis and autoimmune factors. Mutations that reduce STING activity include K224R (Item No. 23593), which reduces ubiquitination of STING thereby disrupting its localization within the cell, and the double mutation G230A, R293Q (Item No. 23592), which reduces the IFN response. A T596A mutation present in the mouse strain Goldenticket leads to a complete loss of STING protein and lack of a type I IFN response to infection by <em>Listeria</em>.


Catalog Number: (76544-506)
Supplier: Cayman Chemical Company
Description: A Certified Reference Material


Catalog Number: (76544-332)
Supplier: Cayman Chemical Company
Description: A Certified Reference Material


Catalog Number: (76544-380)
Supplier: Cayman Chemical Company
Description: A Certified Reference Material


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
To process your orders without delay, please provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:

  • State issued document with your organization's Federal Tax ID Number
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  • City or County issued Business License
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  • Any other ID issued by the State that includes the business name & address

* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.

-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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