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Tofacitinib (CP-690550) citrate

Supplier: Selleck Chemicals
Description: Tofacitinib citrate (CP-690550 citrate) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively.

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(S)-Citalopram oxalate

Catalog Number: (103543-382)
Supplier: Selleck Chemicals
Description: Escitalopram oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
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Imiquimod 99%

Catalog Number: (101759-612)
Supplier: Selleck Chemicals
Description: Imiquimod is a novel synthetic agent with immune response modifying activity.
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GSK1070916 >97%

Catalog Number: (101759-288)
Supplier: Selleck Chemicals
Description: GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM
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Pimamicin ~99%

Supplier: Selleck Chemicals
Description: Pimaricin ( synonym Natamycin), a natural and versatile anti-fungal agent during fermentation by the bacterium <i>Streptomyces natalensis</i>, commonly found in soil, with little to no flavour interference.

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GSK1120212 ~99.5%

Supplier: Selleck Chemicals
Description: Trametinib is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2.

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Tadalafil

Catalog Number: (101763-000)
Supplier: Selleck Chemicals
Description: Tadalafil is a PDE-5 inhibitor with IC<sub>50</sub> of 1.8 nM.
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CB1954 (Tretazicar)

Supplier: Selleck Chemicals
Description: CB1954(Tretazicar) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD(P)H quinone oxidoreductase 2.

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1,4-Butanediol dimethanesulfonate ≥99.90%

Catalog Number: (103539-572)
Supplier: Selleck Chemicals
Description: Busulfan, Purity: 99.90 %, Cas number: 55-98-1, Molecular Weight: 246.3, Form: powder, cell cycle non-specific alkylating antineoplastic agent, DMSO Solubility: 49 mg/mL (198.94 mM), Storage: -20 deg C, Size: 50MG
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Ciclesonide 99.32%

Supplier: Selleck Chemicals
Description: Ciclesonide is a glucocorticoid used to treat obstructive airway diseases.

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Raltegravir

Supplier: Selleck Chemicals
Description: Raltegravir is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000 fold selectivity for HIV-1 IN over several related Mg<sup>2+ </sup>dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human α-, β-, γ-polymerases.

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(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide ~99%

Supplier: Selleck Chemicals
Description: PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with an IC50 of 0.33 nM, roughly 500-fold more potent than CI-1040 on the phosphorylation of ERK1 and ERK2.

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PD-1/PD-L1 Inhibitor 1 ≥99.50%

Catalog Number: (103547-356)
Supplier: Selleck Chemicals
Description: A small-molecule inhibitor of PD-1/PD-L1 interaction with IC50 of 6 nM
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Posaconazole 99%

Supplier: Selleck Chemicals
Description: Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM.

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Cladribine 99.5%

Catalog Number: (101757-882)
Supplier: Selleck Chemicals
Description: Cladribine is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43, 0.75 and 0.18 μM, respectively
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MLN-9708

Supplier: Selleck Chemicals
Description: MLN9708 gets hydrolyzed to its biologically active form MLN2238, on exposure to aqueous solutions or plasma

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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