NEBNext® Enzymatic Methyl-seq v2 Conversion Module

Supplier: New England Biolabs (NEB)

E8020L E8020S
77938-736EA 699.05 USD
77938-736 77938-738
NEBNext® Enzymatic Methyl-seq v2 Conversion Module
Nucleic Acid Reagents Next Generation Sequencing Reagents

NEBNext Enzymatic Methyl-seq (EM-seq) is a high-performance enzyme-based alternative to bisulfite conversion for the identification of 5mC and 5hmC.



  • High efficiency conversion

  • 0.1 to 200 ng input range
  • Minimal DNA damage
  • Minimized GC bias
  • 5mC and 5hmC detection


Unlike bisulfite conversion, this highly efficient method minimizes DNA damage, resulting in superior detection of methylated cytosines, with fewer sequencing reads. The new NEBNext Enzymatic Methyl-seq v2 Conversion Module has a wider input range (as low as 100 pg) than the original EM-seq Conversion Module.



For use in Illumina sequencing workflows, we recommend use of the NEBNext Enzymatic Methyl-seq v2 Kit instead of this module. The full kit includes the EM-seq Adaptor, which has been optimized for high performance in the EM-seq workflow, as well as the high-efficiency NEBNext Ultra II library prep reagents, and these components are not included in the Conversion Module.


Order Now


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR