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NEBNext® Enzymatic Methyl-seq v2 Kit

Supplier: New England Biolabs (NEB)

NEBNext® Enzymatic Methyl-seq v2 Kit

NEBNext® Enzymatic Methyl-seq v2 Kit

E8015L E8015S

77938-732EA 3021.7 USD

77938-732 77938-734

NEBNext® Enzymatic Methyl-seq v2 Kit

Nucleic Acid Reagents Next Generation Sequencing Reagents

NEBNext Enzymatic Methyl-seq (EM-seq) is a high-performance enzyme-based alternative to bisulfite conversion for the identification of 5 mC and 5 hmC.

Superior sensitivity of detection of 5mC and 5hmC
0.1 to 200 ng input range
Detection of more CpGs with fewer sequencing reads
Even GC coverage
Index primers supplied separately

Unlike bisulfite conversion, this highly efficient method minimizes DNA damage, resulting in superior detection of methylated cytosines, with fewer sequencing reads. The new NEBNext Enzymatic Methyl-seq v2 Kit has a wider input range (as low as 100 pg) and a faster, more streamlined workflow than the original EM-seq kit.

The NEBNext Enzymatic Methyl-seq v2 Kit includes conversion reagents, library prep reagents and the EM-seq Adaptor. Multiple sets of the required index primers (NEBNext LV Unique Dual Index Primers) are available separately, enabling greater flexibility in multiplexing.

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