The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening (HTS) 24 and 96-well and plates utilizing our innovative EVOM technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
Automated measurement of tissue resistance of transwell cell cultures provides the advantages of speed and precision, minimizes the chances of contamination, and ensures the rapid availability of measured resistance data. EVOM™ Auto produces a low AC current that omits any adverse physiological effects of the measurement technique on the samples and is specially designed for the non-destructive, high throughput screening of epithelial/endothelial cellular physiology (e.g., confluence of cellular monolayers, barrier integrity of cell cultures, cytotoxicity).
Electrodes available for 24 or 96-well HTS plates - Measure 24 or 96-wells, a column at a time (electrode array measures a column). Save time by automating your process and move through a plate quickly.
Easy switch options for different plate types - By simply plugging in the right electrode array and matching plate adapter key, fast and easy switch between different HTS plate types (e.g., Corning 24, Corning 96) is possible. The users can perform experiments on different platforms (24 or 96 HTS plates or different 96 HTSs) analyze samples using the same system.
Automate your measurements - Streamline your workflow. Minimizes human errors.
Three rinse locations - You may rinse your electrodes multiple times during a measuring sequence. Take control of your protocol and define the sequence you need.
Crash protection - System automatically detects a misalignment and pauses measurements to prevent equipment damage. Minimizes probe damage and avoids costly repairs.
Auto-detection of electrode head - System automatically detects your electrode and configures its position and software options for your plate. Hardware setup is easy and requires no configuration.
Intuitive touchscreen interface with browser-based software - Programming your sequences is simple with simple selection options. Easy-to-navigate system saves time when configuring sequences.
Confirm or create a custom plate profile - Can adjust the programmed coordinates. With complete control of the system, you can fine tune the programming as desired (e.g., plate type, sample depth).
Ability to save three plate coordinates per plate type (e.g., Corning 96) - Multiple (three) users can operate the instrument using their individual saved settings. Date and time stamps of the user plate profile changes help to keep track if the plate profiles were changed. Ensure consistent and error free measurements.
Store all your data or export to Excel - You can analyze your data in a manner suitable to your workflow. Flexibility to access and manage your data.
Number of rinse stations - Three; Minimum sample reading time - 1 s; Control device for running software - Tablet, laptop, desktop with Wi-Fi adapter; Output data - CSV/Microsoft® Excel
Applications: Epithelial and endothelial barrier studies, confluence, cytotoxicity, lung viral infection, Blood Brain Barrier (BBB), lung in vitro models for COVID studies, intestine, kidney and liver tissues.
Certifications: CE, CSA and UL certified.
