Nα-(p-Toluenesulfonyl)-DL-lysine chloromethyl ketone hydrochloride, Calbiochem®
Supplier: MilliporeSigma
616382-50MG
616382-250MG
80057-628EA
113.04
USD
80057-628
80057-626
Nα-(p-Toluenesulfonyl)-DL-lysine chloromethyl ketone hydrochloride, Calbiochem®
Nalpha-(p-Toluenesulfonyl)-DL-lysine chloromethyl ketone hydrochloride
Inhibits trypsin-like serine proteinases
Inactivates trypsin irreversibly without affecting chymotrypsin. Prevents nitric oxide production by activated macrophages by interfering with transcription of the iNOS gene. Blocks cell-cell adhesion and binding of HIV-1 virus to target cells. In macrophages, blocks nitric oxide synthase induced by interferon-[gamma] and lipopolysaccharides (EC50=80µM). Prevents endonucleolysis accompanying apoptotic cell death of HL-60 leukemia cells and normal thymocytes.
Formula:
C₁₄H₂₂Cl₂N₂O₃S |
MDL Number:
MFCD00012513 CAS Number: 4238-41-9 |
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