BAPTA-AM, Calbiochem®
Supplier: MilliporeSigma
Synonyms:
Tetrakis(acetoxymethyl)-1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetate
, 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid Tetrakis(acetoxymethyl) Ester
, BAPTA-AM ester
, Tetrakis(acetoxymethyl) 1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetate
Membrane-permeable form of BAPTA
Can be loaded into a variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA. Prevents cocaine-induced ventricular fibrillations. Abolishes vitamin D3-induced increase in intracellular Ca2+. Induces activation of protein kinase C. Also inhibits thapsigargin-induced apoptosis in rat thymocytes.
Formula:
C₃₄H₄₀N₂O₁₈ MW: 764.69 g/mol |
MDL Number:
MFCD00036696 CAS Number: 126150-97-8 |
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