D-(+)-Trehalose dihydrate ≥98%, white powder
Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Synonyms:
α,α-Trehalose
D-(+)-Trehalose dihydrate is a natural alpha-linked non –reducing disaccharide formed by an α,α-1,1-glucoside bond between two α-glucose units which yields 2 moles of D-glucose upon acid hydrolysis. Has 90% of the calorific content of sucrose.
- Protein stabilizing agent
Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration.
Trehalose has also been used in several biopharmaceutical monoclonal antibody formulations. It is also used as a protein-stabilizing agent in research. Use as a cryoprotectant in a variety of cell freezing media.
Soluble in water (50 mg/mL - clear, colourless solution) or hot alcohol.
Formula:
C₁₂H₂₂O₁₁·2H₂O MW: 378.33 g/mol Melting Pt: 203 °C (lit.) Storage Temperature: Ambient |
MDL Number:
MFCD00071594 CAS Number: 6138-23-4 EINECS: 202-739-6 |
Specification Test Results
Identity Test | Passes |
Purity | ≥98% |
FTIR | Conforms to Standard |
Loss on Drying | 8.5 - 10.5% |
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