β-Nicotinamide adenine dinucleotide, oxidised form (NAD, oxidised form) hydrate ≥98%
Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Synonyms:
Coenzyme I
, beta-DPN
, beta-Diphosphopyridine Nucleotide
, beta-NAD
, beta-Nicotinamide Adenine dinucleotide hydrate, oxidized form
, Cozymase
β-NAD is one of the biologically active forms of nicotinic acid. It occurs in living cells primarily in the oxidized state. Serves as a coenzyme of the dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain. (Merck Index, 12th Ed., No.6429)
Major electron acceptor molecule in biological oxidations. Acts as a coenzyme for hydride-transfer enzymes and a substrate for NAD(+)-consuming enzymes, which include ADP-ribose transferases, poly(ADP-ribose) polymerases, cADP-ribose synthases and sirtuins. Recently reported to be a P2Y11 agonist.
Soluble in water (200 mg/mL)
Formula:
C₂₁H₂₇N₇O₁₄P₂·H₂O Melting Pt: 140 to 142 °C Storage Temperature: Refrigerator |
MDL Number:
MFCD00036253 CAS Number: 53-84-9 EINECS: 200-184-4 Merck Index: 13,06370 |
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