Duplex Dnase

Supplier: New England Biolabs (NEB)

M7635L M7635S
77441-304EA 640 USD
77441-304 77441-306
Duplex Dnase
Nucleic Acid Reagents Next Generation Sequencing Reagents

An engineered double-strand specific DNA endonuclease, dsDNase preferentially degrades double-stranded DNA (dsDNA) over single-stranded DNA (ssDNA) or RNA.


  • Specifically degrades dsDNA in the presence of ssDNA
  • Cleaves DNA strand of DNA:RNA hybrid duplex
  • Isolated from a recombinant sourceRNase-free
  • Supplied with 10X reaction buffer


This specificity toward dsDNA allows the enzyme to degrade contaminating dsDNA while maintaining the integrity of single stranded DNA molecules such as primers and probes within PCR mixes, allowing for efficient decontamination of PCR master mixes. Moreover, dsDNase displays the unique property of cleaving the DNA strand of a DNA:RNA hybrid duplex.


Concentration: 2000 units/ml

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