TCEP-HCl (Tris(2-carboxyethyl)phosphine hydrochloride), powder, Premium Grade, Pierce™

Supplier: 0000013509
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Synonyms: 3,3',3''-Phosphinetriyltripropanoic acid hydrochlorideTris(2-carboxyethyl)phosphine, hydrochlorideTCEP

PG82089 PG82080 PG82089 PG82090 PG82080 PG82090
PIPG82080EA 134.91 USD
CAPIPG82080 PIPG82080 PIPG82090 PIPG82089 CAPIPG82089 CAPIPG82090
TCEP-HCl (Tris(2-carboxyethyl)phosphine hydrochloride), powder, Premium Grade, Pierce™
TCEP-HCl (Tris(2-carboxyethyl)phosphine hydrochloride)

Thermo Scientific Pierce Premium Grade TCEP-HCl is our highest quality formulation of this disulfide reducing agent, specially characterized for applications where product integrity and risk minimization are paramount.


  • TCEP—a thiol-free, odorless yet potent reducing agent for cleaving disulfide bonds
  • High quality—identity and purity confirmed by several tests, including quantitative NMR
  • Product integrity—enhanced level of testing and characterization compared to standard grade
  • Lot retention—ample supply of past lots retained to ensure future process testing
  • Change management—Change Control Notification (CCN) service
  • Consistent manufacture—batch-specific manufacturing documentation review


Compared to the standard grade product, Premium Grade TCEP-HCl provides more clearly defined quality and product support by including (a) increased analytical testing and product characterization, (b) greater batch-specific information and quality assurance review, (c) extensive lot sample retention and (d) change control notification. TCEP-HCl is pure, crystalline Tris(2-carboxyethyl)phosphine hydrochloride, a thiol-free compound that is highly effective at reducing protein and peptide disulfide bonds, as well as being odorless and stable. TCEP selectively and completely reduces even the most stable water-soluble alkyl disulfides over a wide pH range.


Caution: For Research Use Only. Not for use in diagnostic procedures.

Formula: C₉H₁₆ClO₆P
MW: 286.65 g/mol
Storage Temperature: Refrigerator
MDL Number: MFCD00145469
CAS Number: 51805-45-9
UN: 3261
ADR: 8,II

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