SMPH (Succinimidyl-6-((beta-maleimidopropionamido)hexanoate), Pierce™
Supplier: 0000013509
Synonyms:
SMPH
22363
22363
PI22363EA
316.62
USD
CAPI22363
PI22363
SMPH (Succinimidyl-6-((beta-maleimidopropionamido)hexanoate), Pierce™
SMPH (Succinimidyl-6-((beta-maleimidopropionamido)hexanoate)
Thermo Scientific Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (14.2 angstroms).
- Reactive groups: NHS ester and maleimide
- Reactive towards: amino and sulfhydryl groups
- Slightly longer and more soluble than SMPB
- NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
- Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
- Non-cleavable
- Water-insoluble (dissolve first in DMF or DMSO)
Caution: For Research Use Only. Not for use in diagnostic procedures.
Formula:
C₁₇H₂₁N₃O₇ MW: 379.36 g/mol Storage Temperature: Refrigerator |
MDL Number:
MFCD01863460 CAS Number: 367927-39-7 |
Specification Test Results
Product Line | Pierce™ |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Reactive Moiety | Maleimide, NHS Ester |
Spacer | Long |
Form | Powder |
Quantity | 50 mg |
Type | Crosslinker |
Solubility | DMF, DMSO |
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