EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride) crosslinker
Supplier: G-Biosciences
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Danger
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Synonyms:
EDAC hydrochloride
, EDAC HCl
, EDC HCl
, EDC
, 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride
, WSC HCl
, 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
, N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide monohydrochloride
, EDC hydrochloride
, N'-(Ethylcarbonimidoyl)-N,N-dimethylpropane-1,3-diamine monohydrochloride
EDC is a heterobifunctional, water-soluble, zero-length carbodiimide crosslinker that is used to couple carboxyl groups to primary amines. EDC activates carboxyl groups first and forms amine reactive O-acylisourea imtermediate that spontaneously reacts with primary amines to form an amide bond and isourea by-product.
The unstable nature of the intermediate in aqueous solutions makes 2-step coupling, however in conjunction with N-hydroxysuccinimide, a 2-step coupling is possible.
EDC is ideal for peptide immobilization and hapten-carrier protein conjugation
Formula:
C₈H₁₇N₃·HCl MW: 191.7 g/mol Melting Pt: ∼ 113 °C Storage Temperature: Refrigerator |
MDL Number:
MFCD00012503 CAS Number: 25952-53-8 EINECS: 247-361-2 UN: 2811 ADR: 6.1,III |
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