Nucleoside Digestion Mix

Supplier: New England Biolabs
M0649S M0649S
76284-682EA 134 USD
76284-682 CAMSPP-M0649S
Nucleoside Digestion Mix
Enzymes
The Nucleoside Digestion Mix is a mixture of enzymes that provides a convenient one-step method to generate single nucleosides from DNA or RNA.

  • Convenient one-step protocol
  • Digests both DNA and RNA to single nucleosides
  • Low-glycerol formulation significantly reduces glycerol-induced ion suppression during MS analysis

Optimized for quantitative analysis by liquid chromatography-mass spectrometry (LC-MS), this reagent eliminates the need for sequential multi-step, time-consuming digestion protocols. The Nucleoside Digestion Mix digests ssDNA, dsDNA, DNA/RNA hybrids and RNA (except mRNA cap structures) containing epigenetically modified (m5C, hm5C, f5C, ca5C, m4C, m6A, etc.), unnatural, or damaged bases. Moreover, the low-glycerol formulation (<1%) significantly reduces glycerol-induced ion suppression during mass spectrometry analysis.
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