Puromycin dihydrochloride, off-white powder, Cell Culture Grade
Supplier: MP BIOMEDICALS (FKA ICN BIOMED
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Warning
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Synonyms:
(S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamide dihydrochloride
Puromycin is an antibiotic of unique structure and biological activity. It is produced by fermentation using Streptomyces albo-niger. There are four aspects of puromycin's biological activity that are 1) antitumor effect; 2) nephrotoxic action; 3) inhibition of purine and/or protein synthesis and 4) antitrypanosome activity.
Puromycin dihydrochloride is a part of the amino-nucleoside family of antibiotics and is derived from Streptomyces alboniger. It is a broad spectrum antibiotic with antitumor activity, as an inhibitor of protein synthesis and has been used to study transcription regulatory mechanisms that control the sequential and coordinate expression of genes during cell differentiation.
- Grade : Cell Culture Reagent
- Key Applications : Inhibitor of aminopeptidase and enkephalinase.
- Application Areas : Molecular Biology
- Product Type : Biochemicals
- Biochemical Category : Pharmaceuticals
- UV/Visible Absorbance : λ max (0.1N HCl) 268 ± 2 nm
- Presentation : Off-white Powder
- Solubility : Soluble in water (50 mg/mL - clear, colorless solution).
Specification Test Results
Identity Test | Passes |
FTIR | Conforms to Standard |
UV/Vis: l max (0.1N HCl) | 268 ± 2 nm |
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