L-α-phosphatidylinositol-4,5-bisphosphate (from porcine) ≥99%, powder

Supplier: 0000018221

Synonyms: Brain PI(4,5)P2

840046P10MG 840046P25MG 840046P5MG 840046P1MG
100123-250EA 3266 USD
100123-250 100126-684 100121-010 100128-402
L-α-phosphatidylinositol-4,5-bisphosphate (from porcine) ≥99%, powder
L-α-phosphatidylinositol-4,5-bisphosphate

This is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).


As a subsrate in PI 3-kinase, PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 which act as an activator for downstream signaling components such as the protein kinase AKT.

MW: 1096.385 g/mol
Storage Temperature: Freezer
CAS Number: 383907-42-4

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