L-α-phosphatidylinositol-4,5-bisphosphate (from porcine) ≥99%, powder
Supplier: AVANTI POLAR LIPIDS INC MS
Synonyms:
Brain PI(4,5)P2
840046P10MG
840046P25MG
840046P5MG
840046P1MG
100123-250EA
3266
USD
100123-250
100126-684
100121-010
100128-402
L-α-phosphatidylinositol-4,5-bisphosphate (from porcine) ≥99%, powder
L-α-phosphatidylinositol-4,5-bisphosphate
This is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
As a subsrate in PI 3-kinase, PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 which act as an activator for downstream signaling components such as the protein kinase AKT.
MW:
1096.385 g/mol Storage Temperature: Freezer |
CAS Number:
383907-42-4 |
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