EnduRen Live Cell Substrate, Promega

Supplier: Promega Corporation

E6481 E6482 E6485
PAE6481EA 234.35 USD
PAE6481 PAE6482 PAE6485
EnduRen Live Cell Substrate, Promega
Cell Culture Supplements and Additives

An automation-friendly, highly sensitive substrate for Renilla luciferase-based gene reporter and BRET applications.


  • Live-Cell Detection of Renilla Luminescence for up to 24 Hours
  • Engineered coelenterazine for live-cell reporter gene, BRET and RNAi assays
  • Automation-friendly and highly sensitive


EnduRen Live Cell Substrate enables live cell kinetic measurements, streamlining assay development and multiplexing with other lytic assays. EnduRen Live Cell Substrate provides the ability to measure Renilla luciferase luminescence for at least 24 hours after substrate addition, with up to tenfold higher signal-to-background ratios than wildtype coelenterazines. EnduRen Live Cell Substrate is a uniquely engineered coelenterazine with protected oxidation sites, which minimizes substrate degradation and autoluminescence (background) in cell culture, while it extends the luminescent signal to accommodate microplates without the need for auto-injectors. The result is that EnduRen Live Cell Substrate overcomes the key limitations of wildtype coelenterazines by providing an automation-friendly, highly sensitive substrate for Renilla luciferase-based gene reporter and BRET applications.

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