Anti-Double Stranded DNA Mouse Monoclonal Antibody (CF488A) [clone: AE-2]

Supplier: Biotium

BNC880946-500 BNC880946-100
75924-232EA 197.58 USD
75924-232 75924-234
Anti-Double Stranded DNA Mouse Monoclonal Antibody (CF488A) [clone: AE-2]
Antibodies
This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.,Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: Double Stranded DNA
Clonality: Monoclonal
Clone: Clone AE-2
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG3, kappa
Reactivity: Human
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