Anti-TLR2 Mouse Monoclonal Antibody (CF488A) [clone: TLR2/221]

Supplier: Biotium

BNC880221-100 BNC880221-500
75891-914EA 205.77 USD
75891-914 75891-916
Anti-TLR2 Mouse Monoclonal Antibody (CF488A) [clone: TLR2/221]
Antibodies
This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: TLR2
Clonality: Monoclonal
Clone: Clone TLR2/221
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Dog, Human, Monkey
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