Matriptase ELISA, Eagle Biosciences

Supplier: Eagle Biosciences
MAT31-K01
102994-776EA 1340.38 USD
102994-776
Matriptase ELISA, Eagle Biosciences
Assays ELISAs
Matriptase (TADG-15) ELISA detects the cancer antigen Matriptase concentration in human serum.

  • Dynamic Range: 2 - 512 ng/ml
  • Sensitivity: 2 ng/ml
  • Incubation: 2.5 hours

The protein encoded by the Matriptase gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion and metastasis.
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